
Helleborus Therapy
At Cincinnati Integrative Oncology and Functional Medicine (CIOFM), we offer Helleborus Therapy, a botanical treatment used in European integrative oncology for over a century. This unique therapy supports the body’s natural defenses, enhances well-being, and works alongside conventional cancer treatments to improve patient outcomes.
Helleborus niger, also known as the Christmas Rose, is a medicinal plant with a long history of therapeutic use. In integrative cancer care, Helleborus Therapy is valued for its ability to support the immune system, reduce inflammation, and help manage symptoms associated with advanced and metastatic cancers.
A Natural, Supportive Therapy for Cancer Care
Benefits of Helleborus Therapy
Helleborus Therapy offers a range of benefits that support immune function, symptom management, and overall well-being. It works alongside conventional cancer treatments to help patients better tolerate therapy and maintain a higher quality of life.
✔️ Inhibits Cancer Cell Growth While Sparing Healthy Cells
Helleborus contains bioactive compounds that may selectively target cancer cells while protecting healthy tissues, reducing unwanted side effects common with conventional treatments.
✔️ Reduces Inflammation and Supports Immune Function
By modulating the immune system and lowering inflammatory markers, Helleborus Therapy helps create a less hospitable environment for cancer growth and may enhance the body’s natural defenses.
✔️ Improves Circulation, Mental Clarity, and Well-Being
Helleborus has been used to support blood flow, cognitive function, and energy levels, helping patients combat fatigue, brain fog, and overall treatment-related stress.
✔️ Helps Manage Symptoms in Cases of Brain and Lung Metastases
This therapy is often used to provide symptom relief for patients with neurological or respiratory complications, such as headaches, cognitive impairment, shortness of breath, or persistent cough.
✔️ Supports Tumor Stabilization and May Slow Progression
Helleborus Therapy is commonly integrated into treatment plans for aggressive or metastatic cancers, with some patients experiencing a slowing of tumor growth and better disease management over time.
✔️ Alleviates Tumor-Related Pain and Improves Comfort
By reducing swelling, improving circulation, and modulating pain responses, Helleborus Therapy may help relieve tumor-related discomfort and enhance daily function.
While not a replacement for conventional cancer treatments, Helleborus Therapy serves as a powerful complementary therapy that enhances resilience, improves well-being, and supports the body’s natural healing processes.

Helleborus Therapy at CIOFM
Helleborus therapy is primarily administered through subcutaneous (under-the-skin) injections, though in some cases, nebulization or oral drops may be used. The initial dose is administered in-office to ensure proper technique and patient comfort. After this, most patients can self-administer at home with ongoing support from our clinical team. The first dose of subcutaneous is administered in-office.
Pricing may vary depending on the specific formulation, dosage, frequency, and sourcing requirements. Additional shipping costs may apply for European formulations. Inquire with your provider about availability and pricing.
Because Helleborus Therapy requires careful monitoring and personalized dose adjustments, it is available exclusively to CIOFM members. Regular follow-ups ensure treatment is tailored to each patient’s response for optimal efficacy and safety.
Frequently Asked Questions
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Helleborus Therapy is a botanical treatment used in integrative cancer care to support immune function, reduce inflammation, and improve overall well-being. It has been used in European oncology for over a century, often alongside Mistletoe Therapy.
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Helleborus contains bioactive compounds that may help inhibit cancer cell growth, modulate immune responses, improve circulation, and reduce tumor-related symptoms. It is particularly beneficial for patients with advanced or metastatic cancers, including brain and lung involvement.
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No, Helleborus is a complementary therapy that works alongside conventional treatments. It may help improve treatment tolerance, reduce side effects, and enhance overall quality of life but does not replace chemotherapy, radiation, or immunotherapy.
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Helleborus is typically given as small subcutaneous (under-the-skin) injections. In certain cases, nebulization (inhalation) or oral drops may be used, depending on the patient’s condition.
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Yes. The first dose is always administered in-office to ensure proper technique and assess for any potential reactions. After that, most patients can self-administer at home with continued guidance.
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Helleborus Therapy has been used safely in oncology for many years, but like any treatment, it should be administered under medical supervision. Some patients may experience mild injection site reactions or temporary flu-like symptoms, which indicate immune activation.
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Helleborus is not recommended for individuals with a known allergy to Helleborus extracts. It should also be avoided during pregnancy or breastfeeding due to safety concerns.
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Helleborus Therapy is often recommended for patients with aggressive or metastatic cancers, particularly those affecting the brain, lungs, prostate, testicles, and fallopian tubes. It is also used to help manage symptoms associated with lymphedema, ascites, pleural effusions, and bone metastases, including tumor-related pain. While this therapy can be beneficial for a variety of cancers, its application is highly individualized, taking into account each patient’s unique health status and overall treatment plan.
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No, Helleborus Therapy is not typically covered by insurance. It is usually considered an out-of-pocket expense, as it is not FDA-approved in the U.S. However, some health savings accounts (HSAs) or flexible spending accounts (FSAs) may allow reimbursement—check with your provider.
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Because Helleborus requires personalized dose adjustments and ongoing monitoring, it is offered exclusively to CIOFM members. This ensures that patients receive regular follow-ups and tailored treatment for the best outcomes.
Interested in Helleborus Therapy?
If you’re a CIOFM member, contact your provider through the patient portal to discuss whether Helleborus Therapy is a good fit for your treatment plan.
If you’re interested in exploring treatment with Dr. Jamie and the CIOFM team, read our New Patient Information to learn more about how to schedule an initial consultation and get on the path to Membership with our practice.
When you’re ready, schedule a Discovery Call to take the first step!